Biotinylated Human CD52 Protein, His,Avitag™

Source : 

Biotinylated Human CD52, His,Avitag (CD2-H82E8) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ser 36 (Accession # P31358-1).

 

Molecule : CD52

 

Synonyms : CDW52,HE5,CD52,CAMPATH-1 antigen

 

Format : Powder

 

Category : MABSol® Biotin Labeled Proteins

 

Accession : NP_001794.2

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 13.5 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 13.5 kDa. The protein migrates as 16 kDa and 17-22 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.It is widely expressed on the cell surface of immune cells, such as mature lymphocytes, natural killer cells (NK), eosinophils, neutrophils, monocytes/macrophages, and dendritic cells (DCs).ligation of cell surface CD52 molecules may offer costimulatory signals for T-cell activation and proliferation.

 

References :

(1) Zhao Y., et al., 2017 ,Immunogenetics.
(2) Hersh C., et al., 2014, Immunotherapy. 6(3):249-59.
(3) Zinzani PL., et al., 2012, Leuk Lymphoma. 53(5):789-9