Biotinylated Human BTN3A2 Protein, His,Avitag™

Source : 

Biotinylated Human BTN3A2, His,Avitag (BT2-H82E7) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Trp 248 (Accession # P78410-1).

 

Molecule : BTN3A2

 

Synonyms : BT3.2,BT3.3,BTF3,BTF4

 

Format : Powder

 

Category : MABSol® Biotin Labeled Proteins

 

Accession : NP_001184175.1

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 27.3 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 27.3 kDa. The protein migrates as 30-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Butyrophilin subfamily 3 member A2(BTN3A2/BT3.2) mRNA expression by tumoral cells was previously identified as a prognostic factor in a small cohort of high grade serous epithelial ovarian cancer (HG-EOC). We find that the three BTN3A isoforms: BTN3A1, BTN3A2, and BTN3A3, have high structural homology to the B7 superfamily of proteins and exist as V-shaped homodimers in solution, associating through the membrane proximal C-type Ig domain.

 

References :

(1) Le Page C., et al. 2012, PLoS One., 7(6), e38541.
(2) Palakodeti A., et al. 2012, J Biol Chem., 287(39), 32780-90.