BioSim™ anti-Etanercept (Enbrel®) (Human) ELISA Kit

Alternate Name :

Tag Line :

A Sandwich ELISA kit for the qualitative determination of antibody against Cetuximab in human serum or plasma.

Storage Conditions: 4°C

Shelf life: 12 months

Summary :

• Detection method- Absorbance (450 nm)
• Species reactivity- Human
• Application- qualitative determination of antibody against Etanercept (Enbrel) in human serum and plasma

Detection Method: Absorbance (450 nm)

Features & Benefits:

Easy, convenient, sensitive and time-saving method toqualitative determination of antibody against Etanercept (Enbrel) in human serum and plasma.
Cross Reactivity: Etanercept (Enbrel®) infusion camouflages/masks the presence of antibody to Etanercept (ATC) in serum/plasma samples. Therefore, blood sampling time is critical for detection of ATC. It is convenient to obtain blood sample just before the infusion or at least 2 weeks after the infusion of Etanercept.

Description:

Etanercept (Enbrel®) is a therapeutic fusion protein specific for Tumor Necrosis Factor-Alpha (TNF-α) and is used to treat rheumatic arthritis, intestinal disorders, dermatological diseases and cancer. Etanercept specifically binds to TNF alpha and blocks its interaction with cell surface TNF receptors and reduces the inflammation and subsequently improves the patient’s health. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects. BioVision’s BioSimTM anti-Etanercept ELISA kit is designed to detect the antibody against Etanercept with high specificity and sensitivity in biological matrices.