Bilirubin, Direct, 4 x 120 m
- 貨號 Cat. No.
- BQ 007A-CR
- 規格 Size
- 480 Tests
- 品牌 Brand
- BIOQUANT
Description
For the quantitative determination of direct bilirubin in human serum. Bilirubin is a metabolite of the heme portion of heme proteins, mainly hemoglobin. Normally it is excreted into the intestine and bile from the liver. Elevation of total serum bilirubin may occur due to (1) excessive hemolysis or destruction of the red blood cells e.g. hemolytic disease of the newborn, (2) liver diseases e.g. hepatitis and cirrhosis (3) obstruction of the biliary tract e.g., gallstones. There is information in the literature indicating elevated levels of direct bilirubin in patients with liver or biliary tract diseases: even though, total bilirubin levels are normal. Therefore, the greatest diagnostic value of direct bilirubin assays stem from their ability to indicate occult liver disease. Bilirubin reacts with diazotized sulfanilic acid to produce azobilirubin, which has an absorbance maximum at 560 nm in the aqueous solution. The intensity of the color produced is directly proportional to the amount of direct bilirubin concentration present in the sample.
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