Beta-Actin (8H10) Antibody

Actins are highly conserved proteins involved in cell motility that are ubiquitously expressed in eukaryotic cells. There are 3 main actin isoforms in vertebrates: alpha, beta and gamma. The alpha actins are found in muscles and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and mediators of internal cell motility. Defects in beta-actin are a cause of juvenile-onset dystonia, a movement disorder with a neurological basis.