Catalog Number250556 Unit0.1 mg FormatEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Data and Images | DescriptionBreast cancer resistance protein (BCRP) is a xenobiotic transporter with an important role in the exclusion of xenobiotics from the brain. BCRP is also involved in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase int he efflux of rhodamine 123. Product Citations
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Alternate NamesATP-binding cassette sub-family G member 2; Placenta-specific ATP-binding cassette transporter; Mitoxantrone resistance-associated protein; Breast cancer resistance protein; CDw338; CD338; ABCG2; ABCP; BCRP; BCRP1; MXR Accession No.Clonality
Antigen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BCRP.
Application Notes
E: 1:500-1:1,000 WB: 1:200-1:500 IHC: 1:200-1:500 Reacts with :H | M | R | Other
StorageStore at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |