Bcl-10 Antibody
Antibodies
Description
***DISCONTINUED***
B-cell lymphoma/leukemia 10 (Bcl-10) promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. Bcl-10 is an adapter protein between the upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Bcl-10 is a substrate for MALT1. Defects in Bcl-10 are involved in various types of cancer.
B-cell lymphoma/leukemia 10 (Bcl-10) promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. Bcl-10 is an adapter protein between the upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Bcl-10 is a substrate for MALT1. Defects in Bcl-10 are involved in various types of cancer.
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