AZD2281
Chemical Compounds
- 貨號 Cat. No.
- M1664
- 規格 Size
- 10mg,50mg,100mg,500mg
- 品牌 Brand
- No Brand
Description
AZD 2281 (Olaparib, KU-0059436) is a novel, potent orally active PARP (poly ADP-ribose polymerase) inhibitorwith IC50 of 5 and 1 nM for PARP-1and PARP-2 respectively. AZD 2281 (Olaparib, KU-0059436) acts as an inhibitor of the enzyme Poly ADP ribose polymerase (PARP) and is one of the first PARP inhibitors.It induces cancer specific synthetic lethality in homologous recombination repair defective cells, including BRCA-deficient tumors.
