AV-951

Chemical Compounds

貨號 Cat. No.
M1656
規格 Size
10mg,50mg
品牌 Brand
No Brand

Description

AV-951 (Tivozanib) is a potent VEGFR-1, 2 and 3, c-Kit and PDGFR inhibitor with IC50 of 0.21, 0.16, 0.24, 1.63 and 1.72 nM respectively.AV-951 (Tivozanib) blocks the proliferation and migration of endothelial cells in vitro, and suppresses angiogenesis and growth of human tumor xenografts in vivo.

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