AT9283
Chemical Compounds
- 貨號 Cat. No.
- M1655
- 規格 Size
- 5mg,10mg,50mg ,100mg
- 品牌 Brand
- No Brand
Description
AT9283 is a potent inhibitor of several protein kinases, including Aurora A, Aurora B, Janus kinase 2 (JAK2), JAK3, and ABL. AT9283 potently inhibited proliferation and Jak2-related signalling in Jak2-dependent cell lines. The compound also demonstrated significant therapeutic potential in vivo in an ETV6-JAK2 (TEL-JAK2) murine leukaemia model.
