Kits
APRIL (A Proliferation-Inducing Ligand), ELISA
- 貨號 Cat. No.
- K 9411
- 規格 Size
- 96 Tests
- 品牌 Brand
- IDS
Description
| Article number: | K 9411 |
| Method: | ELISA |
| Tests: | 96 Tests |
| Matrix: | Biological liquids |
| Volume: | 100 µl |
| Incubation time: | 16h; 1h; 2h; 2h; 1h; 10-30min |
| Standards: | 1.95-125 ng/ml |
| APRIL - a type II transmembrane protein [250 aa, cytoplasmatic domain: 28aa, transmembrane domain: 21aa, extracellular domain: 201aa] - is considered to be involved in autoimmune and cancer diseases. It stimulates proliferation of tumor cell lines and seems to play a role in tumorgenesis. In general it is involved in B and T cell proliferation, triggers humoral immune responses, activates NF-kB and induces cell death. TACI (transmembrane activator) and BCMA (B-cell maturation antigen) are considered to be receptors for APRIL. APRIL belongs to the TNF-Superfamily which is involved in immune responses and apoptosis. |