APRIL (A Proliferation-Inducing Ligand) ELISA

pAPRIL (A br /
Proliferation-Inducing br /
Ligand) ELISAbr /
nbsp;/p
pimg alt=For Research Use Only src=http://www.alpco.com/img/ruo.gif align=absMiddle / For Research Use Only/p
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div class=prod_spec_box
div class=prod_specbFormat:/b/div
div class=prod_spec_infoELISA / EIA/div
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div class=prod_specSample Type:/div
div class=prod_spec_infoplasma, cell culture/div
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div class=prod_specbSample Size:/b/div
div class=prod_spec_info100 micro;l/div
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div class=prod_specbSize:/b/div
div class=prod_spec_info96 wells/div
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div class=prod_specbRange:/b/div
div class=prod_spec_info15.6 - 1000 ng/ml/div
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div class=prod_specbSensitivity:/b/div
div class=prod_spec_info15.6 ng/ml/div
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div class=prod_specbIncubation Time:/b/div
div class=prod_spec_info6 hour(s) 20 min(s)/div
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pbSummary:/b/p
APRIL - a type II transmembrane protein [250 aa, cytoplasmatic domain: 28aa, transmembrane domain: 21aa, extracellular domain: 201aa] is considered to be involved in autoimmune and cancer diseases. It stimulates proliferation of tumor cell lines and seems to play a role in tumorgenesis. In general it is involved in B and T cell proliferation, triggers humoral immune responses, activates NF-kappa;B and induces cell death.br /
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TACI (transmembrane activator) and BCMA (B-cell maturation antigen) are considered to be receptors for APRIL. APRIL belongs to the TNF-Superfamily which is involved in immune responses and apoptosis./div
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