ApoM (10C3) Antibody

ApoM (Apolipoprotein M) is a 188-amino acid protein (~ 21kDa) is an apolipoprotein and member of the lipocalin protein family. The Apo-proteins are involved in specific binding of cellular receptors, regulation of lipolytic enzymes and the process of lipid exchange. ApoM is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. The N-terminal region of Apo-M contains hydrophobic residues that may promote association with the phospholipid layer of lipoprotein particles. In vitro, Apo-M is glycosylated when translated in the presence of microsomes and remains associated with the microsomes after carbonate treatment. Apo-M is expressed in liver and kidney, is secreted into the bloodstream in HDLs, also found in triglyceride-rich lipoproteins and LDLs.