ApoE3 Antibody

貨號 Cat. No.
5696-100
規格 Size
100 µg

Description

pstrongAntibody Target :/strongApoE3/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bRecombinant human ApoE3/p
pbAccession#: /bNP_000032/p
pbGene ID: /b348/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhu/p
pbApplication: /bWB/p
pbApplication amp; Usage: /bWestern blotting (0.5-4 micro;g/ml). However, the optimal concentrations should be determined individually. Recombinant ApoA1 (Cat. # 4696-100) can be used as a positive control. The antibody recognizes ~34 kDa of human ApoE3. Reactivity to other species has not been tested./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bApoE belongs to a group of proteins that bind reversibly with lipoprotein and play an important role in lipid metabolism. ApoE is an important constituent of all plasma lipoproteins. Itrsquo;s interaction with specific ApoE receptor enables uptake of chylomicron remnants by liver cells, which is an essential step during normal lipid metabolism. It also binds with the LDL receptor (apo B/E). Defects in ApoE are a cause of hyperlipoproteinemia type III. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. E3 is the most common isoform and is present in 40-90% of the population./p

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