ApoA1 Antibody

貨號 Cat. No.
5695-100
規格 Size
100 µg

Description

pstrongAntibody Target :/strongApoA1/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bE. coli expressed recombinant rat ApoA1/p
pbAccession#: /bP04639/p
pbGene ID: /b25081/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) affinity purified rabbit anti-rat A1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /brt/p
pbApplication: /bWB/p
pbApplication amp; Usage: /bWestern blot analysis (0.5-4 micro;g/ml). Recombinant rat ApoA1 (Cat.#: 4695-100) can be use as a positive control. However, the optimal conditions should be determined individually. Other applications have not been determined./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bApoA1 is a 29.0 kDa protein produced in the liver and intestine, and secreted as the predominant constituent of nascent high-density lipoprotein (HDL) particle. ApoA1 which is found exclusively in HDL has a unique ability to capture and solubilize free cholesterol. This ApoA-I ability enables HDL to remove excess peripheral cholesterol and return it to the liver for recycling and excretion. This process, called reverse cholesterol transport, is thought to inhibit atherogenesis. For this reason HDL is also known as the ldquo;good cholesterol.rdquo; The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of ApoA-I (called ApoA1 Milano). Rat ApoA1 s a 27.4 kDa protein of 235 amino acid residues./p

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