Apixaban

Chemical Compounds

貨號 Cat. No.
M1649
規格 Size
10mg,50mg, 200mg
品牌 Brand
No Brand

Description

Apixaban is a direct Human Factor Xa inhibitor with Ki of 0.08 nM. Apixaban prolongs the clotting times of normal human plasma with the concentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM and 0.4 μM in vitro. Apixaban significantly inhibits factor Xa activity with IC50 of 0.22 μM in rabbit ex vivo.

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