API-5 Antibody
Antibodies
- 貨號 Cat. No.
- 251620
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA 、 IHC 、 WB
- Reactivity
- Human 、 Mouse
Description
Apoptosis inhibitor 5 (API-5) is an antiapoptotic factor that plays a role in protein assembly. API-5 negatively regulates ACIN1. By binding to ACIN1, API-5 suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. API-5 also efficiently suppresses E2F1-induced apoptosis. Low levels of API-5 enhance the cytotoxic action of the chemotherapeutic drugs.
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