APE-1 Polyclonal Ab

貨號 Cat. No.
3405-100
規格 Size
100 ug

Description

pimg src=http://www.biovision.com/Merchant2/graphics/00000001/antibody-stock-miva.jpg alt= //p
pfont size=2 /font/p
pbHOST:/b Rabbit/p
pbIMMUNOGEN:/b Synthetic peptides of human APE/p
pbFORMULATION: /b100 ug (0.5 mg/ml) Protein G purified rabbit anti-APE-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal./p
pbSPECIES REACTIVITY: /bhuman/p
pbSTORAGE CONDITIONS: /bStore at -20oC. For long-term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbBACKGROUND: /bHuman apurinic (apyrimidinic) endonuclease/redox-factor 1 (APE/Ref-1) is involved in the repair of DNA damage as well as in the transcriptional regulation of genes. Ape1/ref-1 has been shown to stimulate the DNA binding activity of numerous transcription factors that are involved in cancer promotion and progression. APE/Ref-1 is part of the cellular response to oxidative stress and protects cells from the genotoxic and cytotoxic effect of oxidizing agents./p
pbSPECIFICITY: /bThe antibody detects the 37 kDa human APE-1./p
pbAPPLICATION AND USAGE: /bThe antibody can be used for Western blotting (1-4 ug/ml). However, the optimal conditions should be determined individually. HeLa cell lysate can be used as a positive control. USAGE: The product is/p
pbFor Research Use Only. Not to be used in human. /b/p

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