APC Peptide

h1 class=titleAPC Peptide/h1
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h4Catalog Number/h4
pstrong350494/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4Price/h4
pstrong$50.00/strong/p
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h4Description/h4
pThe adenomatous polyposis coli protein (APC) is a tumor suppressor that promotes rapid degradation of catenin-beta 1 (CTNNB1) and participates in Wnt signaling. The GSK3-beta protein kinase regulates its activity by phosphorylation. APC binds to PDZ domains of DLG1 and 3, to catenins, axin and MAPRE protein family including the EB members./p
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h4Format/h4
pnbsp;/p
pEach vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect./p
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h4Data and Images/h4
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h4Product Citations/h4
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h4Recommended Products/h4
pbr /
a href=http://abbiotec.com/antibodies/apc-antibody-1200132 APC Antibody/abr /
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h4Alternate Names/h4
pAdenomatous polyposis coli protein; protein APC; DP2.5/p
h4Accession No./h4
pa class=accession-link href=http://www.expasy.ch/uniprot/P25054 target=_blankP25054/abr /
a class=accession-link href=http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=proteinamp;id=53759122 target=_blankNP_000029/abr /
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h4MW/h4
p1990.2 g/mol/p
h4Sequence/h4
pThe synthetic peptide used to raise the antibody Cat. No. 200132 is selected from a sequence within the N-term region of human APC. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended./p
h4Composition/h4
pnbsp;/p
pC101H148N22O31S1/p
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h4Purity/h4
pPurity gt; 80% by HPLC/p
h4Solubility/h4
pDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile./p
h4Storage/h4
pStore at -20deg;C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20deg;C./p
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