Apaf-1 (C-term) Antibody
Antibodies
- 貨號 Cat. No.
- 250542
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA 、 IHC 、 WB
- Reactivity
- Human 、 Rat
Description
Apoptosis protease activating factor-1 (Apaf-1) mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3) by forming oligomer upon binding with cytochrome c and dATP. Oligomeric Apaf-1 binds to pro-caspase 9 through their N-terminal CARD domains releasing mature caspase-9.
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