Antithrombin III (7E11) Antibody

Catalog Number

250396

Unit

0.2 mg

 

Format

Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Data and Images

Description

Antithrombin III (AT III) is a single chain glycoprotein of molecular mass 58 kDa with four glycosylation sites and three intra-molecular disulfide bonds. AT III is normally present in human plasma at a concentration of approx. 12.5 mg/dl. It is the major inhibitor of thrombin. Inactivation of thrombin by AT-III occurs by formation of a covalent bond resulting in an inactive 1:1 stoichiometric complex between the two components.  This antibody is specific for the native form of human AT III.

Product Citations

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Alternate Names

Antithrombin-III; ATIII; SERPINC1; AT3

Accession No.

P01008

 

Clonality

7E11

Antigen

Antithrombin III isolated from human plasma (1)

Application Notes

Product Cat. No. 250396 reacts strongly in ELISA with native AT III coated directly onto the microtiter well, or in sandwich ELISA as detection antibody with a polyclonal capture antibody. Product Cat. No. 250396 also reacts in western blot with AT III. 

E: 1:32,000

WB: 1:1,000

Reacts with  :H

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment.