Antithrombin III (2 E10) Antibody

Catalog Number

250392

Unit

0.2 mg

 

Format

Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Data and Images

Description

Antithrombin III (AT III) is a single chain glycoprotein of molecular mass 58 kDa with four glycosylation sites and three intra-molecular disulfide bonds. AT III is normally present in human plasma at a concentration of approx. 12.5 mg/dl. It is the major inhibitor of thrombin. Inactivation of thrombin by AT-III occurs by formation of a covalent bond resulting in an inactive 1:1 stoichiometric complex between the two components. This antibody is specific for human AT III in native and denatured forms.

Product Citations

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Alternate Names

Antithrombin-III; ATIII; SERPINC1; AT3

Accession No.

P01008

 

Clonality

2 E10

Antigen

Antithrombin III isolated from human plasma (1)

Application Notes

Product Cat. No. 250392 reacts strongly in ELISA with both native and denatured AT III directly coated onto the microtiter well, or in sandwich ELISA as detection antibody with a polyclonal capture antibody.

E: 1:16,000

Reacts with  :H

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment.