Anti-UbcH12
- 貨號 Cat. No.
- A-655
- 規格 Size
- 200 μl
- 品牌 Brand
- Boston Biochem
Description
Anti-UbcH12
rabbit polyclonal
Product Information
200 μl
PBS pH 7.4, 20% glycerol.
Full-length, highly purified human UbcH12 protein.
Protein A affinity purified rabbit polyclonal antibody.
Use & Storage
Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.
Recommended dilution range for Western blot analysis is 1:100 to 1:1000.
Catalog #: A-655
Anti-UbcH12
Product Source:
rabbit polyclonal
also known as Ubc12,hUbc12, UBE2M
NEDDylation requires the coordinated activities of UbcH12 and the APP-BPI/Uba3 activating enzyme. This E2 enzyme mediates the covalent conjugation of the ubiquitin-like protein NEDD8 to a limited number of cellular proteins such as Cdc53/Cul1 and other members of the cullin family (which are structural subunits of the Skp1-based and elongin B/C-based families of ubiquitin protein ligases). The NEDD8 pathway is essential for cell viability in fission yeast, and in mammalian cells it is essential for cell cycle progression and morphogenesis.
Product Information
Quantity:
200 μl
Stock:
PBS pH 7.4, 20% glycerol.
Antigen:
Full-length, highly purified human UbcH12 protein.
Supplied:
Protein A affinity purified rabbit polyclonal antibody.
Use & Storage
Storage:
Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.
Specificity:
Recommended dilution range for Western blot analysis is 1:100 to 1:1000.