Anti-TPO (Anti-Thyroid Peroxidase Antibody) ELISA

pAnti-TPO (Anti-Thyroid br /
Peroxidase Antibody) ELISA/p
pimg alt=For Research Use Only align=absMiddle src=http://www.alpco.com/img/ruo.gif / For Research Use Only/p
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div class=prod_specbFormat:/b/div
div class=prod_spec_infoELISA / EIA/div
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div class=prod_specSample Type:/div
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div class=prod_specbSample Size:/b/div
div class=prod_spec_info100 micro;l/div
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div class=prod_specbSize:/b/div
div class=prod_spec_info96 wells/div
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div class=prod_specbRange:/b/div
div class=prod_spec_info5 IU/ml - 2000 IU/ml/div
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div class=prod_specbSensitivity:/b/div
div class=prod_spec_info3 IU/ml/div
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div class=prod_specbIncubation Time:/b/div
div class=prod_spec_info1 hour(s) 15 min(s)/div
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pbSummary:/b/p
Thyroid peroxidase (TPO), a glycoprotein with a molecular weight of 100 kD, is identified as the primary antigenic component of microsomes in thyroid cells. TPO catalyses the iodination of tyrosine in thyroglobulin during the biosynthesis of triiodothyronine and thyroxine (T3 and T4 respectively). Disorders of the thyroid gland are frequently caused by autoimmune reactions. TPO and thyroglobulin are the most important targets for autoimmune attacks. The major thyroid autoimmune diseases are Hashimoto's thyroiditis and Graves' disease. In virtually all cases of Hashimoto's disease and in the majority cases of Graves' disease, anti-TPO levels are elevated. A high level of anti-TPO helps to confirm the diagnosis of these thyroid autoimmune disorders.
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