Anti-SUMO
- 貨號 Cat. No.
- A-712
- 規格 Size
- 200 μl
- 品牌 Brand
- Boston Biochem
Description
Anti-SUMO
rabbit polyclonal
Product Information
200 μl
PBS pH 7.4
Full-length, highly purified human SUMO-1 protein.
Use & Storage
Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.
Recommended dilution range for Western blot analysis is 1:500 to 1:1500. Antibody cross-reacts with SUMO1, SUMO2 and SUMO3 proteins, but not ubiquitin, Nedd8 or ISG15 proteins.
Catalog #: A-712
Anti-SUMO
Product Source:
rabbit polyclonal
The ubiquitin-like SUMO proteins are conjugated to a variety of proteins in the presence of UbcH9 and the Aos1/Uba2 (yeast) or SAE1/SAE2 (human) activating enzyme. Sumolyation can occur without the requirement of a specific E3 ligase activity, where SUMO is transferred directly from UbcH9 to specific substrates. Sumolyated substrates are primarily localized to the nucleus (RanGAP-1, RANBP2, PML, p53, Sp100, HIPK2) but there are also cytosolic substrates (IκBα, GLUT1, GLUT4). SUMO modification has been implicated in functions such as nuclear transport, chromosome segregation and transcriptional regulation.
Product Information
Quantity:
200 μl
Stock:
PBS pH 7.4
Antigen:
Full-length, highly purified human SUMO-1 protein.
Use & Storage
Storage:
Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.
Specificity:
Recommended dilution range for Western blot analysis is 1:500 to 1:1500. Antibody cross-reacts with SUMO1, SUMO2 and SUMO3 proteins, but not ubiquitin, Nedd8 or ISG15 proteins.