Anti-rat IgA Antibody

IgA (immunoglobulin A) is a 160 kDa glycosylated protein produced as a monomer or as a J chain-linked dimer. Secretory IgA (sIgA) are composed of 2-4 IgA monomers linked by the J chain (15 kDa) and a secretory component (70 kDa). Monomeric IgA constitutes 5-15% of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces such as saliva, gastrointestinal secretion, bronchial fluids and milk. Mucosal IgA plays a major role in host defence by neutralising infectious agents at mucosal surfaces.