Anti-Rabbit IgG, HRP-Linked Antibody

Antibody Target: Anti-Rabbit IgG-HRP

Alternative Name: Anti-Rabbit IgG, HRP-Linked Antibody, HRP linked secondary antibody

Host: Goat

Antibody Type: Polyclonal

Isotype: Goat IgG

Antibody Form: Affinity Purified Antibody

Immunogen: N/A

Accession#: N/A

Gene ID: N/A

Appearance: Colorless liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) immunoaffinity purified rabbit anti-GFRα-2 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.

Purification:

Species Reactivity:

Application:

Application & Usage: Western blot analysis (1 µg/ml) and a 52 kDa band should be detected. However, the optimal conditions should be determined individually.

Storage Temp.: -20 °C

Shipping: gel pack

Shelf Life: 12 months

Background Descriptions: Members of the glial cell line-derived neurotropic factor (GDNF) family, including GDNF and neuturin (NTN), play key roles in the control of vertebrate neuron survival and differentiation. Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRα, which is a cell surface receptor for NTN. The cDNA encoding NTNRα from human, rat, chicken and mouse have been cloned recently. NTNRα was also termed GDNFRβ Ret ligand 2 (RETL2), or TGF-β-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRα-2 recently. GFRα-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF. Thus, NTN, GFRα-2 and the Ret PTK from a complex to transduce NTN signal and to mediate NTN function.

Handling: The antibody solution should be gently mixed before use.