Proteins and Peptides
Anti-PPP1R12A / MYPT1 Antibody (HRP)
- 貨號 Cat. No.
- LS-C548251-100
- 規格 Size
- 100 µl
- 品牌 Brand
- LSBio
Description
pnbsp;/p
h3 class=srcSitecss_AntibodyDetailBoxHeadingPaddingH3 style=padding: 6px 0px 1px 8px; margin: 2px 0px; color: rgb(26, 86, 158); font-size: 16px; font-family: Calibri, Verdana, Arial, Helvetica, sans-serif;Details/h3
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div class=srcSitecss_ProductDetailLeftColumnDIV style=width: 600px; font-family: Verdana, Arial, Helvetica, sans-serif;
div class=srcSitecss_AntibodyDetailBoxDIV style=border: 1px solid rgb(192, 192, 192); border-radius: 6px; padding: 6px 4px 6px 6px; margin-right: 4px;
table
tbody
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td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelTarget:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Human PPP1R12A / MYPT1/td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelHost:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Rabbit/td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelReactivity:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Human, Mouse, Rat, Chickennbsp;span class=srcSitecss_AntibodyDetailBoxCommentSPAN style=color: rgb(128, 128, 128); font-size: 10px;(tested or 100% immunogen sequence identity)/span/td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelClonality:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;IgG Polyclonal/td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelConjugations:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Horseradish Peroxidase. Also available conjugated withnbsp;a href=https://www.lsbio.com/antibodies/anti-ppp1r12a-antibody-mypt1-antibody-ap-wb-western-ls-c510111/523672AP/a,nbsp;a href=https://www.lsbio.com/antibodies/anti-ppp1r12a-antibody-mypt1-antibody-apc-wb-western-ls-c518298/531859APC/a,nbsp;a href=https://www.lsbio.com/antibodies/anti-ppp1r12a-antibody-mypt1-antibody-biotin-wb-western-ls-c528147/541708Biotin/a,nbsp;a href=https://www.lsbio.com/antibodies/anti-ppp1r12a-antibody-mypt1-antibody-fitc-wb-western-ls-c538109/551671FITC/a,nbsp;a href=https://www.lsbio.com/antibodies/anti-ppp1r12a-antibody-mypt1-antibody-pe-wb-western-ls-c656276/669841PE/a./td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelPurification:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Protein A purified/td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelModifications:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Unmodified/td
/tr
/tbody
/table
/div
h3 class=srcSitecss_AntibodyDetailBoxHeadingPaddingH3 style=padding: 6px 0px 1px 8px; margin: 2px 0px; color: rgb(26, 86, 158); font-size: 16px; font-family: Calibri, Verdana, Arial, Helvetica, sans-serif;Applications/h3
div class=srcSitecss_AntibodyDetailBoxDIV style=border: 1px solid rgb(192, 192, 192); border-radius: 6px; padding: 6px 4px 6px 6px; margin-right: 4px;label class=srcSitecss_AntibodyAssayListLABEL style=font-weight: bold; vertical-align: top; width: 100px; display: inline-block; padding-left: 5px;Approved:/labelnbsp;
ul class=srcSitecss_AntibodyAssayListUL style=display: inline-block; margin: 0px; padding-bottom: 3px; width: 400px;
liWestern blot/li
li(applications tested for the base form of this product only)/li
/ul
nbsp;/div
h3 class=srcSitecss_AntibodyDetailBoxHeadingPaddingH3 style=padding: 6px 0px 1px 8px; margin: 2px 0px; color: rgb(26, 86, 158); font-size: 16px; font-family: Calibri, Verdana, Arial, Helvetica, sans-serif;Specificity and Use/h3
div class=srcSitecss_AntibodyDetailBoxDIV style=border: 1px solid rgb(192, 192, 192); border-radius: 6px; padding: 6px 4px 6px 6px; margin-right: 4px;
table
tbody
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelImmunogen:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Synthetic peptide corresponding to aa845-855, C-EKRRS[pT]GVSFW of chicken MYPT1 with an N-terminal cysteine added for conjugation purposes (Q90623). Phosphorylation site corresponds to Thr853 in human MYPT1./td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelSpecificity:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Recognizes recombinant human truncated MYPT1 phosphorylated on Thr850, MW ~80kD. Species cross-reactivity: mouse, rat and chicken./td
/tr
/tbody
/table
/div
h3 class=srcSitecss_AntibodyDetailBoxHeadingPaddingH3 style=padding: 6px 0px 1px 8px; margin: 2px 0px; color: rgb(26, 86, 158); font-size: 16px; font-family: Calibri, Verdana, Arial, Helvetica, sans-serif;Packaging/h3
div class=srcSitecss_AntibodyDetailBoxDIV style=border: 1px solid rgb(192, 192, 192); border-radius: 6px; padding: 6px 4px 6px 6px; margin-right: 4px;
table
tbody
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelPresentation:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;PBS, pH 7.2. No preservative added./td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelStorage:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Store at 4deg;C./td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelRestrictions:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;For research use only./td
/tr
/tbody
/table
/div
/div
div class=srcSitecss_ProductDetailLeftColumnDIV style=width: 600px; font-family: Verdana, Arial, Helvetica, sans-serif;
div style=margin-right: 4px;
h3 class=srcSitecss_AntibodyDetailBoxHeadingPaddingH3 style=padding: 6px 0px 1px 8px; margin: 2px 0px; color: rgb(26, 86, 158); font-size: 16px; font-family: Calibri, Verdana, Arial, Helvetica, sans-serif;About PPP1R12A / MYPT1/h3
div class=srcSitecss_AntibodyDetailBoxDIV style=border: 1px solid rgb(192, 192, 192); border-radius: 6px; padding: 6px 4px 6px 6px; margin-right: 4px;label style=font-weight: bold;Uniprot:nbsp;/labela href=http://www.expasy.org/uniprot/o14974 target=_blankO14974/anbsp;label style=font-weight: bold;NCBI:/labelnbsp;a href=http://www.ncbi.nlm.nih.gov/nuccore/nm_002480 target=_blankNM_002480/anbsp;a href=http://www.ncbi.nlm.nih.gov/protein/np_002471.1 target=_blankNP_002471.1/a
plabel style=font-weight: bold;Synonyms:/labelnbsp;PPP1R12A Antibody, M130 Antibody, MYPT1 Antibody, MBS Antibody, Myosin binding subunit Antibody/p
label style=font-weight: bold;Description:/labelnbsp;Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells.
div class=srcSite_ProductInfoColumnMoreLink style=padding: 10px 0px 4px; margin-right: 4px;a href=https://www.lsbio.com/targets/ppp1r12a-mypt1/g8997(More About PPP1R12A / MYPT1)/a/div
/div
/div
/div
h3 class=srcSitecss_AntibodyDetailBoxHeadingPaddingH3 style=padding: 6px 0px 1px 8px; margin: 2px 0px; color: rgb(26, 86, 158); font-size: 16px; font-family: Calibri, Verdana, Arial, Helvetica, sans-serif;Details/h3
pnbsp;/p
div class=srcSitecss_ProductDetailLeftColumnDIV style=width: 600px; font-family: Verdana, Arial, Helvetica, sans-serif;
div class=srcSitecss_AntibodyDetailBoxDIV style=border: 1px solid rgb(192, 192, 192); border-radius: 6px; padding: 6px 4px 6px 6px; margin-right: 4px;
table
tbody
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelTarget:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Human PPP1R12A / MYPT1/td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelHost:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Rabbit/td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelReactivity:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Human, Mouse, Rat, Chickennbsp;span class=srcSitecss_AntibodyDetailBoxCommentSPAN style=color: rgb(128, 128, 128); font-size: 10px;(tested or 100% immunogen sequence identity)/span/td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelClonality:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;IgG Polyclonal/td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelConjugations:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Horseradish Peroxidase. Also available conjugated withnbsp;a href=https://www.lsbio.com/antibodies/anti-ppp1r12a-antibody-mypt1-antibody-ap-wb-western-ls-c510111/523672AP/a,nbsp;a href=https://www.lsbio.com/antibodies/anti-ppp1r12a-antibody-mypt1-antibody-apc-wb-western-ls-c518298/531859APC/a,nbsp;a href=https://www.lsbio.com/antibodies/anti-ppp1r12a-antibody-mypt1-antibody-biotin-wb-western-ls-c528147/541708Biotin/a,nbsp;a href=https://www.lsbio.com/antibodies/anti-ppp1r12a-antibody-mypt1-antibody-fitc-wb-western-ls-c538109/551671FITC/a,nbsp;a href=https://www.lsbio.com/antibodies/anti-ppp1r12a-antibody-mypt1-antibody-pe-wb-western-ls-c656276/669841PE/a./td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelPurification:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Protein A purified/td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelModifications:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Unmodified/td
/tr
/tbody
/table
/div
h3 class=srcSitecss_AntibodyDetailBoxHeadingPaddingH3 style=padding: 6px 0px 1px 8px; margin: 2px 0px; color: rgb(26, 86, 158); font-size: 16px; font-family: Calibri, Verdana, Arial, Helvetica, sans-serif;Applications/h3
div class=srcSitecss_AntibodyDetailBoxDIV style=border: 1px solid rgb(192, 192, 192); border-radius: 6px; padding: 6px 4px 6px 6px; margin-right: 4px;label class=srcSitecss_AntibodyAssayListLABEL style=font-weight: bold; vertical-align: top; width: 100px; display: inline-block; padding-left: 5px;Approved:/labelnbsp;
ul class=srcSitecss_AntibodyAssayListUL style=display: inline-block; margin: 0px; padding-bottom: 3px; width: 400px;
liWestern blot/li
li(applications tested for the base form of this product only)/li
/ul
nbsp;/div
h3 class=srcSitecss_AntibodyDetailBoxHeadingPaddingH3 style=padding: 6px 0px 1px 8px; margin: 2px 0px; color: rgb(26, 86, 158); font-size: 16px; font-family: Calibri, Verdana, Arial, Helvetica, sans-serif;Specificity and Use/h3
div class=srcSitecss_AntibodyDetailBoxDIV style=border: 1px solid rgb(192, 192, 192); border-radius: 6px; padding: 6px 4px 6px 6px; margin-right: 4px;
table
tbody
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelImmunogen:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Synthetic peptide corresponding to aa845-855, C-EKRRS[pT]GVSFW of chicken MYPT1 with an N-terminal cysteine added for conjugation purposes (Q90623). Phosphorylation site corresponds to Thr853 in human MYPT1./td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelSpecificity:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Recognizes recombinant human truncated MYPT1 phosphorylated on Thr850, MW ~80kD. Species cross-reactivity: mouse, rat and chicken./td
/tr
/tbody
/table
/div
h3 class=srcSitecss_AntibodyDetailBoxHeadingPaddingH3 style=padding: 6px 0px 1px 8px; margin: 2px 0px; color: rgb(26, 86, 158); font-size: 16px; font-family: Calibri, Verdana, Arial, Helvetica, sans-serif;Packaging/h3
div class=srcSitecss_AntibodyDetailBoxDIV style=border: 1px solid rgb(192, 192, 192); border-radius: 6px; padding: 6px 4px 6px 6px; margin-right: 4px;
table
tbody
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelPresentation:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;PBS, pH 7.2. No preservative added./td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelStorage:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;Store at 4deg;C./td
/tr
tr
td class=srcSitecss_ProductDetailLabelTD style=width: 120px; font-weight: bold; vertical-align: top;labelRestrictions:/label/td
td class=srcSitecss_ProductDetailBoxRightTD style=padding-left: 10px; vertical-align: top;For research use only./td
/tr
/tbody
/table
/div
/div
div class=srcSitecss_ProductDetailLeftColumnDIV style=width: 600px; font-family: Verdana, Arial, Helvetica, sans-serif;
div style=margin-right: 4px;
h3 class=srcSitecss_AntibodyDetailBoxHeadingPaddingH3 style=padding: 6px 0px 1px 8px; margin: 2px 0px; color: rgb(26, 86, 158); font-size: 16px; font-family: Calibri, Verdana, Arial, Helvetica, sans-serif;About PPP1R12A / MYPT1/h3
div class=srcSitecss_AntibodyDetailBoxDIV style=border: 1px solid rgb(192, 192, 192); border-radius: 6px; padding: 6px 4px 6px 6px; margin-right: 4px;label style=font-weight: bold;Uniprot:nbsp;/labela href=http://www.expasy.org/uniprot/o14974 target=_blankO14974/anbsp;label style=font-weight: bold;NCBI:/labelnbsp;a href=http://www.ncbi.nlm.nih.gov/nuccore/nm_002480 target=_blankNM_002480/anbsp;a href=http://www.ncbi.nlm.nih.gov/protein/np_002471.1 target=_blankNP_002471.1/a
plabel style=font-weight: bold;Synonyms:/labelnbsp;PPP1R12A Antibody, M130 Antibody, MYPT1 Antibody, MBS Antibody, Myosin binding subunit Antibody/p
label style=font-weight: bold;Description:/labelnbsp;Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase. Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho. The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells.
div class=srcSite_ProductInfoColumnMoreLink style=padding: 10px 0px 4px; margin-right: 4px;a href=https://www.lsbio.com/targets/ppp1r12a-mypt1/g8997(More About PPP1R12A / MYPT1)/a/div
/div
/div
/div
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