ANTI HUMAN TR BETA1

Thyroid hormone receptor beta (TRb, THRB; NR1A2) is a member of nuclear hormone receptors. The ligands for TRb are the thyroid hormones, which exist in two forms: T4 (3,5,3',5'-tetraiodo-L-thyronine) and T3 (3,5,3'- tri-iodo-L-thyronine). TRb plays critical roles in the differentiation, growth, metabolism and physiology of a wide variety of tissues. The major partners of TRs are the RXRs, which strongly enhance their ability to bind to specific DNA sequences and contribute to the specificity of action of TR.