ANTI HUMAN PR ISOFORM B

Progesterone receptor (PR; NR3C3) is a member of steroid receptor (GR, AR, MR, ER). PR binds progesterone. PR is expressed in uterus, ovary, vagina, fallopian tubes and breast. PR plays a central role in diverse reproductive events associated with establishment and maintenance of pregnancy, alveolar development in the breast, and sexual behavior. Two isoforms of this receptor have been identified, PR-A and PR-B, 94 and 114 kDa in size, respectively. PR was shown that PR-A and PR-B isoforms can form homodimers as well as heterodimers.