ANTI HUMAN HNF4 ALPHA7

Antibodies

貨號 Cat. No.
PP-H6939-00
規格 Size
1
品牌 Brand
Iwai North America
Application 應用
IHC 、 IP 、 W 、 WB
Reactivity
Human

Description

Hepatocyte nuclear factor 4 alpha (HNF4, HNF4a; NR2A1) is a member of orphan nuclear receptor. HNF4a is expressed in the liver, kidney, intestine and pancreas. Mutation of HNF4a in humans has been associated with maturity-onset diabetes of the young type 1 (MODY1). HNF4 binds to DNA as an exclusive homodimer. The HNF4a gene is alternatively spliced and may generate up to nine different isoforms, HNF4a1 through HNF4a9.

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