ANTI HUMAN GR COMMON
Antibodies
- 貨號 Cat. No.
- PP-H8031-00
- 規格 Size
- 1
- 品牌 Brand
- Iwai North America
- Application 應用
- IP 、 WB
- Reactivity
- Human
Description
Glucocorticoid receptor (GR; NR3C1) is a member of steroid receptor (AR, ER, MR, PR). GR is expressed in almost all human tissues and organs.GR binds to its sequences as an homodimer. Two different forms, GRa and GRb, differing in their C-terminal parts were isolated. GRa is the classic GR that binds to glucocorticoids and transactivates or transrepresses glucocorticoid-responsive promoters. GRb does not bind glucocorticoids.
