ANTI-HUMAN ATF7IP
Antibodies
- 貨號 Cat. No.
- BMR00348
- 規格 Size
- 1
- 品牌 Brand
- Iwai North America
- Reactivity
- Human
Description
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. Required to stimulate histone methyltransferase activity of SETDB1 and facilitate the conversion of dimethylated to trimethylated H3 'Lys-9'. The complex formed with MBD1 and SETDB1 represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. [UniProtKB?Function]
