Anti-Galanin Receptor Type 3 (extracellular)
- 貨號 Cat. No.
- AGR-013
- 規格 Size
- 50 μl 0.2ml
Description
Anti-Galanin Receptor Type 3 (extracellular)
| Product#: | AGR-013 |
| Sizes: |
| 50 µl |
| 0.2 ml |
| Host: | ||
Rabbit.
|
| Epitope: |
Peptide SYYGTVRYGALELC corresponding to amino acid residues 159-172 of mouse Galanin receptor type 3(Accession O88853). |
 |
| Putative epitope location: |
| 2nd extracellular loop. |
| Homology: |
| Rat and human identical. |
| Reactivity Confirmed: |
Rat. |
Applications:
| Western Blotting: |
 | Western blot analysis of Galanin receptor type 3 in rat brain membrane: 1. Anti-Galanin Receptor Type 3 (extracellular) antibody (#AGR-013),(1:200). 2. Anti-Galanin Receptor Type 3(extracellular) antibody, preincubated with the control peptide antigen. |
Galanin is a neuropeptide, consisting of 29-30 amino acid residues, involved in the regulation of cognition, mood, feeding, seizure activity and pain. Galanin exerts its action via three known Galanin receptors, the Galanin receptor type 1 (GALR1), Galanin receptor type 2 (GALR2) and Galanin receptor type 3 (GALR3). The Galanin receptors belong to the G-protein-coupled receptor superfamily.1-4
Based on mRNA, the GALR1 is predominantly distributed in the central nervous system, spinal cord and dorsal root ganglia while GALR2 is abundant in both central and peripheral nervous system. GALR3 mRNA is distributed in peripheral tissues such as heart, spleen, and testis. However, its expression in the brain is still controversial.4,5
Alomone Labs is pleased to offer a highly specific antibody directed against an extracellular epitope of mouse Galanin Receptor type 3 (GALR3). The Anti-GALR3 (extracellular) antibody (#AGR-013) can be used for Western blot analysis application. It has been designed to recognize GALR3 from mouse, rat and human samples.