Anti-Caγ2
- 貨號 Cat. No.
- ACC-012
- 規格 Size
- 50 μl 0.2ml
Description
Anti-CaVg2
| Product#: | ACC-012 |
| Sizes: |
| 50 µl |
| 0.2 ml |
| Host: |
| Rabbit |
| Epitope: |
Peptide (C)RATD YLQAS AITRI PS, corresponding to residues 213-228 of mouse Cavg2 (Accession O88602). |
 |
| Putative epitope location: |
| Intracellular, C-terminal part. |
| Homology: |
| Rat, human - identical. |
Applications:
| Western Blotting: |
 | Western blotting of rat brain membranes: 1. Anti-Cavg2 antibody (#ACC-012) (1:200). 2. Anti-Cavg2 antibody, preincubated with the control peptide antigen. |
| References: |
| 1. Arikkath, J. and Campbell, K. P. (2003) Curr. Opin. Neurobiol. 13, 298. |
The g subunit protein is an auxiliary subunit of the CaV (voltage dependent calcium) channel multimer complex. g1 was first identified in skeletal muscle as a part of the proteins complex purified as the DHP receptor. Eight g subunit isoforms were identified in mammalian genoms and they share some sequence as well as structure homology.1 g subunit contains four transmembrane helixes, with intracellular N and C termini. Usually their association with the pore-forming a1 subunit results in reduced current amplitude. g2 is expressed in brain (where it is belived to interact also with AMPA receptors).1
Alomone Labs offers a polyclonal antibody directed against an intracellular epitope at the C-terminus of the auxiliary subunit CaVg2.