Amylin Peptide
- 貨號 Cat. No.
- 350015
- 規格 Size
- 1 mg
- 品牌 Brand
- Abbiotec
Description
h1 class=titleAmylin Peptide/h1
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h4Catalog Number/h4
pstrong350015/strong/p
h4Unit/h4
pstrong1 mg/strong/p
h4Price/h4
pstrong$325.00/strong/p
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pnbsp;/p
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h4Description/h4
pAmylin, also called Islet or insulinoma amyloid polypeptide (IAPP), is a 37-amino acid monomeric polypeptide isolated from pancreatic amyloid, which is commonly found in the islet of patients with diabetes mellitus type II and in insulinomas. Amylin is derived from a larger propeptide precursor of 89 amino acids in humans. Immunostaining of amylin is found in islet amyloid and in cells of the islets of Langherans, where it colocolizes with insulin in islet B cells. This peptide corresponds to full-length amylin (residues 34-70 of human amylin precursor) with a Cys2-Cys7 disulfide bridge and an amidated C-terminus end./p
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h4Format/h4
pnbsp;/p
pEach vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt./p
pnbsp;/p
h4Data and Images/h4
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h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pbr /
nbsp;/p
h4Alternate Names/h4
pIslet amyloid polypeptide; Amylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptide; IAPP/p
h4Accession No./h4
pa class=accession-link href=http://au.expasy.org/uniprot/P10997 target=_blankP10997/abr /
a class=accession-link href=http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=proteinamp;id=4557655 target=_blankNP_000406/abr /
nbsp;/p
h4MW/h4
p3906.3 g/mol/p
h4Sequence/h4
pHuman: Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 or KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2 (Cys2-Cys7)/p
h4Composition/h4
pnbsp;/p
pC165H262O50N56S2/p
pnbsp;/p
h4Purity/h4
pPurity gt; 95% by HPLC/p
h4Solubility/h4
pWe recommend using 100% dimethyl sulfoxide (DMSO)./p
h4Storage/h4
pStore at -20deg;C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20deg;C./p
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h4Catalog Number/h4
pstrong350015/strong/p
h4Unit/h4
pstrong1 mg/strong/p
h4Price/h4
pstrong$325.00/strong/p
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pnbsp;/p
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div class=descriptionpad
h4Description/h4
pAmylin, also called Islet or insulinoma amyloid polypeptide (IAPP), is a 37-amino acid monomeric polypeptide isolated from pancreatic amyloid, which is commonly found in the islet of patients with diabetes mellitus type II and in insulinomas. Amylin is derived from a larger propeptide precursor of 89 amino acids in humans. Immunostaining of amylin is found in islet amyloid and in cells of the islets of Langherans, where it colocolizes with insulin in islet B cells. This peptide corresponds to full-length amylin (residues 34-70 of human amylin precursor) with a Cys2-Cys7 disulfide bridge and an amidated C-terminus end./p
/div
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tbody
tr
td valign=top width=50%
h4Format/h4
pnbsp;/p
pEach vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt./p
pnbsp;/p
h4Data and Images/h4
/td
td valign=top
h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pbr /
nbsp;/p
h4Alternate Names/h4
pIslet amyloid polypeptide; Amylin; Diabetes-associated peptide; DAP; Insulinoma amyloid peptide; IAPP/p
h4Accession No./h4
pa class=accession-link href=http://au.expasy.org/uniprot/P10997 target=_blankP10997/abr /
a class=accession-link href=http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=proteinamp;id=4557655 target=_blankNP_000406/abr /
nbsp;/p
h4MW/h4
p3906.3 g/mol/p
h4Sequence/h4
pHuman: Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 or KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY-NH2 (Cys2-Cys7)/p
h4Composition/h4
pnbsp;/p
pC165H262O50N56S2/p
pnbsp;/p
h4Purity/h4
pPurity gt; 95% by HPLC/p
h4Solubility/h4
pWe recommend using 100% dimethyl sulfoxide (DMSO)./p
h4Storage/h4
pStore at -20deg;C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20deg;C./p
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