Amrubicin

Amrubicin is a synthetic anthracycline which has been shown in preclinical studies to have broad-spectrum anti-tumor activity and a lower potential for cardiotoxicity as compared to doxorubicin. Amrubicin Shows Promise in Relapsed or Refractory Small Cell Lung Cancer.Amrubicin acts by inhibiting topoisomerase II, and has been compared in clinical trials with topotecan, a Topoisomerase I inhibitor.It has also been studied for the treatment of bladder carcinoma and gastric cancer. Amrubicin appears to have significant activity against invasive thymoma.