Alpha-Synuclein (N-term) Antibody

The synucleins alpha, beta and gamma are presynaptic proteins abundant in neurons. Alpha-synuclein, a component of Alzheimer's disease amyloid plaques, is localized to neuronal cell bodies and synapses. Defects in alpha-synuclein are the cause of Parkinson disease type 1 and 4, Lewy body dementia, Alzheimer's disease, and Hallervorden-Spatz syndrome.