Alpha-Fetoprotein (7C6) Antibody

Catalog Number

250333

Unit

0.2 mg

 

Format

Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Data and Images

Description

Alpha-fetoprotein (AFP) is a serum protein produced by hepatocytes. AFP levels are used as a tumor marker for hepatomas and germ cell tumors, and the serum concentration has prognostic significance in other diseases. Levels of AFP is 0.6-9.3 kIU/L in blood from normal individuals under the age of 40. Concentrations raise with age and during pregnancy AFP consists of one single polypeptide chain of 590 aminoacids with MW 65 kDa. This antibody is specific for human AFP. Cross-reactivity with other species or similar molecules has not been investigated.

Product Citations

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Alternate Names

Alpha-fetoprotein;  Alpha-fetoglobulin;  Alpha-1-fetoprotein

Accession No.

P02771

 

Clonality

7C6

Antigen

Human alpha-fetoprotein isolated from amniotic fluid

Application Notes

Product Cat. No. 250333 reacts strongly with AFP when used as detection antibody in sandwich ELISA in combination with a polyclonal antibody against human AFP. Antibody Ka<3.8, determined as concentration of antibody giving half-maximal binding to hepatoma-AFP bound to solid phase (unit: 108 L/mol).

E: 1:20,000

Reacts with  :H

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment.