Alpha CrossLaps® (CTX-I) ELISA

The ALPHA CrossLaps® (CTX-I) ELISA is an enzyme-linked immunosorbent assay for the quantification of non-isomerized fragments of C-terminal telopeptides of Type-I collagen (α CTX-I) in human urine. The ALPHA CrossLaps® (CTX-I) ELISA is intended for use as an indicator of degradation of non-isomerised bone collagen and may be used as an aid in the identification of skeletal metastases in patients with breast and prostate cancer. In addition, the ALPHA CrossLaps® (CTX-I) ELISA may be applied to humans as an aid in the diagnosis of Paget’s disease and the monitoring of anti-resorptive therapy in patients with Paget’s disease.