Alpha-CGRP (A1) Antibody

Catalog Number

250237

Unit

0.2 mg

 

Format

Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Data and Images

Description

Calcitonin gene-related peptide is a 37 amino-acid vasoactive neuropeptide (MW 3789) widely expressed throughout the central and peripheral nervous system. CGRP has potent vasodilatory effects probably serving as a regulator of regional blood flow, in addition to a variety of other cellular effects. This antibody binds human alpha-CGRP. Based on inhibition ELISA, this antibody cross-reacts up to 12% with human beta-CGRP and human amylin, whereas there is weak cross-reaction (<4%) with rat alpha-CGRP.

Product Citations

Recommended Products

250238 Alpha-CGRP (A2) Antibody

 

Alternate Names

Calcitonin gene-related peptide 1 (Precursor);  CGRP-1;  Alpha-type CGRP

Accession No.

P06881

 

Clonality

NA

Antigen

Synthetic human alpha-CGRP coupled to carrier

Application Notes

Product Cat. No. 250237 binds free human alpha-CGRP in solution. The ELISA dilution guideline applies to human alpha-CGRP coated directly at 1.0  ug/ml. Product Cat. No. 250237 (as biotinylated detection antibody) forms a sandwich ELISA pair with Product Cat. No. 250238 (as capture antibody) for measuring human alpha-CGRP, giving a detection limit of 0.13 nmol/l in an unoptimized buffer assay.

E: 1:8,000

Reacts with  :H

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment.