Alpha-1 Antitrypsin Antibody

Catalog Number

250475

Unit

0.1 mg

 

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Description

Alpha-1-antitrypsin (AAT) is an inhibitor of serine proteases. Although AAT's primary target is elastase, the enzyme has also a moderate affinity for plasmin and thrombin. AAT inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. AAT deficiency is related to emphysema and liver disease.

Product Citations

Recommended Products

Alternate Names

Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; SERPINA1; AAT; PI

Accession No.

P01009

 

Clonality

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human AAT.

Application Notes

E: 1:500-1:1,000

WB: 1:100-1:500

IHC: 1:200-500

Reacts with  :H | M | R | Other

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.