ALK5 Inhibitor II

Chemical Compounds

貨號 Cat. No.
M1859
規格 Size
10mg,25mg,50mg
品牌 Brand
No Brand

Description

ALK5 Inhibitor is a potent and selective inhibitor of the TGF-β RI kinase with IC50 values of 0.004 and 0.023 μM for ALK5 autophosphorylation and ALK5 binding, respectively. It enhances the efficiency of cellular reprogramming. ALK5 Inhibitor affects a range of related kinases selectively, including p38 MAPK, GSK3 and JNK1 (IC50 > 16 μM).

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