Akt Inhibitor

Alternate Name/Synonyms: 1L-6-Hydroxymethyl-chiro-inositol2-[(R)-2-O-methyl-3-O-octadecylcarbonate]

Appearance: White to off-white solid

Formulation: N/A

CAS Number: N/A

Molecular Formula: C₃₀H₅₈O₁₀

Molecular Weight: 578.8

Purity: ≥98%

Solubility: DMSO

Storage Temp.: -20°C

Shipping Conditions: gel pack

Description: Potent inhibitor of Akt (PKB) (ICâ‚…â‚€ = 2 µM). Weak inhibitor of phosphatidylinositol 3-kinase (PI3-K) (ICâ‚…â‚€ = 83 µM). Has been shown to inhibit the growth of the following cancer cell lines: HeLa (ICâ‚…â‚€ = 2.5 µM), HT-29 (ICâ‚…â‚€ = 10 µM), MCF-7 (ICâ‚…â‚€ = 1.2 µM), and PC-3 (ICâ‚…â‚€ = 2.0 µM).

Handling: Protect from air and moisture