AIF Antibody

Antibodies

貨號 Cat. No.
250464
規格 Size
0.1 mg
品牌 Brand
Abbiotec
Application 應用
ELISA 、 IHC 、 WB
Reactivity
Human 、 Mouse

Description

Apoptosis-inducing factor (AIF) is a mitochondrial protein that translocates to the nucleus upon induction of apoptosis. It has been demonstrated that AIF causes DNA fragmentation and chromatin condensation, and induces the release of cytochrome c and caspase-9 from mitochondria. Release of AIF from mitochondria was shown to be prevented by over-expression of Bcl-2, a protein involved in mitochondrial permeability.

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