Adrenomedullin Antibody

Catalog Number

250239

Unit

0.2 mg

 

Format

Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Data and Images

Description

Human adrenomedullin is a 52 amino-acid peptide (mw 6029) with the physiological effect of lowering blood pressure through vasodilatation, an effect it shares with calcitonin gene-related peptide (CGRP) and vasoactive intestinal peptide (VIP). In addition adrenomedullin has other cardiovascular effects including growth and development of both cardiovascular tissues and bone, and has effects in the central nervous system connected with the regulation of fluid balance. This antibody binds human adrenomedullin and shows no cross-reaction with CGRP.

Product Citations

Recommended Products

Alternate Names

Adrenomedullin; ADM; AM

Accession No.

P35318

 

Clonality

NA

Antigen

Synthetic human/rat NPY coupled to carrier with glutaraldehyde

Application Notes

The ELISA dilution guideline applies to adrenomedullin coated directly at 1.0  ug/mL. The binding of Product Cat. No. 250239 to coated ADM is not inhibited by full-length adrenomedullin in solution up to a concentration of 1 µmol/L, but is inhibited by adrenomedullin (22-52) in solution.

E: 1:40,000

Reacts with  :H

Storage

Store at 4°C. Product is guaranteed 6 months from the date of shipment.