ADNP Antibody

Catalog Number

250460

Unit

0.1 mg

 

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Data and Images

Description

Activity-dependent Neuroprotective Protein (ADNP) is a potential transcription factor that mediates some of the neuroprotective peptide VIP-associated effects involved in normal growth and cancer proliferation. ADNP is mainly expressed in the cerebellum and hippocampus with lower levels in lung, kidney, intestine and testis. The neuroprotective peptide provides neuroprotection at sub-femtomolar concentrations against toxicity associated with tetrodoxin (electrical blockade), beta-amyloid peptide (Alzheimer's disease neurotoxin), N-methyl-aspartate (excitotoxicity), and human immunodeficiency virus (HIV) envelope protein.

Product Citations

Recommended Products

Alternate Names

ADNP; Activity-dependent neuroprotective homeobox protein; Activity-dependent neuroprotective protein; ADNP1

Accession No.

Q9H2P0

 

Clonality

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ADNP protein.

Application Notes

E: 1:500-1:1,000

WB: 1:200-1:500

IHC: 1:200-1:500

IP:Use at an assay dependent concentration

Reacts with  :H | M | R

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.