Adipophilin, human, recombinant

Alternate Names / Synonyms: Adipose differentiation-related protein, ADRP, ADFP, MGC10598.

Gene Symbol: PLIN2

Accession #: Q99541

Gene ID: 123

Gene Source: Human

Recombinant Host: E. coli

Appearance: Lyophilized protein

Physical Form: Lyophilized from 0.5 mg/ml solution containing 20mM Tris pH 7.5, and 20 mM NaCl,

Molecular Weight: 49.0 kDa

Purity by SDS-PAGE: ≥95%

Purity by HPLC: N/A

Endotoxin Level: N/A

Biological Activity: N/A

Reconstitution: Add de-ionized water to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.

Storage Temp.: -20°C

Shipping: Gel pack

Background Information: Adipophilin is a 49 kDa protein that belongs to the PAT family (perilipin, adipophilin, TIP47, S3-12 and OXPAT), which comprises proteins involved in the coating of lipid droplets. ADFP is expressed in lipid droplets of vitamin A-storing hepatic stellate cells and additionally in lipid droplets of steatotic hepatocytes. ADFP expression has a role in clear cell renal carcinoma differentiation. Most recently, it has been discovered that patients with kidney cancers had high levels of ADFP in their urine, suggesting that ADFP could be an excellent marker for kidney cancer.

Handling: Centrifuge the vial prior to opening.