Adiponectin (Mouse)(HMW Total) ELISA

pAdiponectin (Mouse)(HMW amp; br /
Total) ELISAbr /
nbsp;/p
pimg alt=For Research Use Only src=http://www.alpco.com/img/ruo.gif align=absMiddle / For Research Use Only/p
div class=prod_head_infohr /
/div
div class=prod_spec_box
div class=prod_specbFormat:/b/div
div class=prod_spec_infoELISA / EIA/div
/div
div class=prod_spec_box
div class=prod_specSample Type:/div
div class=prod_spec_infoserum, plasma, EDTA plasma/div
/div
div class=prod_spec_box
div class=prod_specbSample Size:/b/div
div class=prod_spec_info5 micro;l*/div
/div
div class=prod_spec_box
div class=prod_specbSize:/b/div
div class=prod_spec_info96 wells/div
/div
div class=prod_spec_box
div class=prod_specbRange:/b/div
div class=prod_spec_info0.125-8.0 ng/ml/div
/div
div class=prod_spec_box
div class=prod_specbSensitivity:/b/div
div class=prod_spec_info0.032 ng/ml/div
/div
div class=prod_spec_box
div class=prod_specbIncubation Time:/b/div
div class=prod_spec_info3 hour(s)/div
div class=prod_spec_info
pbSummary:/b/p
p* = The recommended starting sample volume in this kit is between 5 and 10 micro;l. See package insert for details (Section 7: Sample Volume Adjustment)./p
br /
pAdiponectin circulates as multiple isoformssup1/sup and is widely recognized as a key protein involved in insulin regulation and metabolic syndrome. Of the different multimers, the high-molecular-weight (HMW) form of adiponectin activates adenosine monophosphate activated protein kinase phosphorylation most effectivelysup1/sup, and HMW levels, or the ratio of HMW to total adiponectin, are more meaningful than the total adiponectin level for predicting insulin resistance and the development of metabolic syndromesup2/sup./p
br /
pRecently, an ELISA system was developed for the selective quantification of human adiponectin oligomers using protease pretreatmentsup3/sup, and this kit reflects a similar system for simultaneous detection of mouse HMW and total adiponectin. sup4/sup/p
br /
p1) Hada Y, et al. Biochem Biophys Res Commun 2007; 356: 487-93.br /
2) Hara K, et al. Diabetes Care 2006; 29: 1357-62br /
3) Ebinuma H, et al. Clin Chim Acta 2006; 372: 47-53br /
4) Ebinuma H, et al. Clin Chim Acta 2009; 401: 181-3/p
pnbsp;/p
pnbsp;/p
/div
/div