Adiponectin ELISA

Adiponectin-ELISA is designed to measure the concentration of adiponectin in samples of rodent or human origin. Decreased levels of adiponectin, an adipose-derived protein with anti-inflammatory, anti-artherogenic and insulin-sensitizing properties, are linked to obesity, insulin resistance and Type 2 diabetes. Serum adiponectin levels are elevated in patients with overt diabetic nephropathy and may be due to either an increase in synthesis of adiponectin in adipose tissue secreted into the circulation or to a reduction in adiponectin clearance. Quantification of adiponectin in serum or urine may be used as a marker for renal insufficiency and tubular damage especially in overt diabetic nephropathy.